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Filtered Search Results
Inorganic Ventures 1000µg/mL MAGNESIUM 125mL
Inorganic Ventures' 1000 ppm (µg/mL) Magnesium for IC is a 125mL certified reference material set in a nitric acid matrix for stability. This magnesium standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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Apexbio Technology LLC Pyriproxyfen 95737-68-1 1g
Pyriproxyfen (CAS 95737-68-1) is a small-molecule inhibitor targeting insect juvenile hormone receptors It is designed to interfere with hormone-mediated developmental signaling thereby disrupting endocrine-regulated metamorphosis in insect larvae Pyriproxyfen exerts its biological activity primarily through binding to juvenile hormone receptors impeding physiological maturation and reproduction cycles in target arthropod populations In laboratory experiments pyriproxyfen demonstrates inhibitory activity with IC50 values ranging from approximately 0 1 to 10 M depending on insect species and experimental conditions Based on these pharmacological properties pyriproxyfen holds research potential in agricultural pest management and public health applications involving vector-borne diseases transmitted by arthropods
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Waters Corp Waters PIC Reagent, B5, 25 mL, 5 Vials, 240+ nm UV
Waters PIC Reagent, B5, 25 mL, 5 Vials, 240+ nm UV
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Apexbio Technology LLC PDE5-IN-7 139756-21-1 1g
PDE5-IN-7 (CAS 139756-21-1) is a selective inhibitor of phosphodiesterase 5 (PDE5) functioning by impeding PDE5 enzymatic activity and thereby reducing the hydrolysis of cyclic guanosine monophosphate (cGMP) This results in elevated intracellular cGMP levels In biochemical assays PDE5-IN-7 demonstrates potent inhibition of PDE5 with an IC50 of approximately 5 nM while displaying significantly lower potency against PDE1 (IC50 300 nM) Due to its selectivity and potency PDE5-IN-7 is valuable for investigating cGMP-mediated signaling vasorelaxation mechanisms and pathways involved in cardiovascular physiology
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Inorganic Ventures 1000µg/mL IODIDE 500mL
Inorganic Ventures' 1000 ppm (µg/mL) Ammonium Iodide for IC is a 500mL certified reference material set in a water / stabilizer matrix for stability. This iodide standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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Apexbio Technology LLC Etravirine (TMC125) 269055-15-4 1g
Etravirine (TMC125) (CAS 269055-15-4) is a small-molecule inhibitor targeting HIV-1 reverse transcriptase It is designed to block the activity of this enzyme thereby preventing HIV-1 viral replication Etravirine exerts its biological activity primarily through direct binding to HIV-1 reverse transcriptase as a non-nucleoside reverse transcriptase inhibitor (NNRTI) inducing conformational changes that reduce the enzyme s catalytic efficiency In cell-based assays Etravirine demonstrates potent inhibition of HIV-1 replication with reported IC50 values typically in the low nanomolar to sub-nanomolar range Based on these pharmacological properties Etravirine holds research potential in antiviral activity profiling resistance mutation analysis and mechanistic studies of reverse transcriptase function and HIV replication pathways
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Waters Corporation IonSABRE Positive Ion Sensitivity Standard, 5 mg, Reference, System Performance
This Mass Spectrometry standards kit is designed for system assessment. It includes Ion Sabre positive ion Sensitivity: 1 X 5mg 17-alpha-hydroxyprogesterone and 1 X 4 ml Amber Glass with sample prep document Screw Top Vial.
- Separation mode: reversed phase
- Detection method: MS
- Formulation: solid
- Storage condition: room temperature
- System type: MS
- Shelf life: 24 months
- Shipping condition: ambient
- Mass: 5 mg
- Type: reference
- Application: system performance
- Product type: standards
- Units per package: 1 pk
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Waters Corp Waters Chlorate Ion Calibration Standard, 1000 mg/L, 125 mL, H2O
Waters Chlorate Ion Calibration Standard, 1000 mg/L, 125 mL, H2O
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Apexbio Technology LLC Enoxolone 471-53-4 1g
Enoxolone (CAS 471-53-4) also known as glycyrrhetinic acid is a principal component of licorice with reported antiviral and antifungal activities It modulates corticosteroid signaling by inhibiting 11 -hydroxysteroid dehydrogenase (11 -HSD) isoenzymes in hepatic and renal tissues In rats the IC50 values for 18 -enoxolone-mediated inhibition of 11 -HSD activity are 0 09 M in liver and 0 36 M in kidney homogenates Enoxolone also suppresses 11 -HSD activity in human JEG-3 choriocarcinoma cells This compound is used in biomedical research to study glucocorticoid metabolism mineralocorticoid receptor specificity and enzyme regulation in steroidogenesis
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SCP Science NITRATE-N 1000PPM 125ML
This item has a minimum qty of 2 per supplier requirements.
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Apexbio Technology LLC Fluazinam 79622-59-6 1g
Fluazinam (CAS 79622-59-6) is a small-molecule inhibitor targeting fungal mitochondrial respiratory chain complex II (succinate dehydrogenase SDH) It is designed to disrupt electron transfer during cellular respiration thereby impairing ATP production crucial for fungal cell viability Fluazinam exerts its biological activity primarily through inhibition of mitochondrial SDH In biochemical assays Fluazinam demonstrates inhibitory activity with reported IC50 values ranging from approximately 0 03 to 0 12 M against fungal SDH Based on these pharmacological properties Fluazinam holds research potential in investigating antifungal resistance mechanisms mitochondrial respiration impairment energy metabolism alterations and oxidative stress-related signal transduction pathways
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Apexbio Technology LLC Guaifenesin 93-14-1 1g
Guaifenesin (93-14-1) is a small-molecule expectorant designed to modulate respiratory epithelial cell secretion thereby regulating mucus viscosity and bronchial mucus clearance in the respiratory tract Guaifenesin exerts its biological activity primarily through enhancement of respiratory tract hydration and reduction of mucus viscosity via direct modulation of respiratory epithelial cells Based on these pharmacological properties guaifenesin holds research potential in studies of mucus clearance mechanisms bronchial secretion regulation and potential application in neuromuscular activity modulation with exploratory investigations in fibromyalgia symptom management and reproductive biology
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Apexbio Technology LLC Lamotrigine 84057-84-1 1g
Lamotrigine (CAS 84057-84-1) is a small molecule anticonvulsant that acts primarily as a voltage-gated sodium channel blocker stabilizing neuronal membranes and inhibiting repetitive neuronal firing Research indicates that lamotrigine inhibits serotonin (5-HT) uptake with reported IC50 values of 240 M in human platelets and 474 M in rat brain synaptosomes These dual actions on sodium channels and 5-HT transport underline its utility in studies investigating the modulation of excitatory neurotransmission and synaptic function in neurological and psychiatric conditions
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Apexbio Technology LLC AICAR phosphate 681006-28-0 1g
AICAR phosphate (CAS 681006-28-0) also known as Acadesine is an activator of AMP-activated protein kinase (AMPK) In studies involving B-cell chronic lymphocytic leukemia (B-CLL) cells AICAR phosphate induces apoptosis in a dose-dependent manner with an EC50 of approximately 380 60 M This apoptotic effect is associated with caspase activation and mitochondrial cytochrome c release Notably AICAR phosphate at concentrations of 2 4 mM has minimal impact on T lymphocyte viability from B-CLL patients indicating selective activity These properties make it a valuable tool for research on AMPK signaling and B-cell malignancy mechanisms
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Apexbio Technology LLC (-)-Fenchone 7787-20-4 1g
(-)-Fenchone is a naturally derived bicyclic monoterpenoid ketone with defined chirality Due to its intrinsic chiral structure (-)-Fenchone serves as a valuable precursor in synthetic pathways leading to biologically active compounds and is utilized in stereospecific catalysis It interacts with olfactory receptor systems enabling its application in research on neural signaling and sensory perception mechanisms Additionally (-)-Fenchone is employed in studies of structural modification of natural products secondary plant metabolite biosynthesis and screenings of biologically active molecules
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